Prof. Dotan is the Director of the Division of Gastroenterology at the Rabin Medical Center, Petah Tikva, Israel, affiliated with the Sackler Faculty of Medicine, Tel Aviv, Israel. Prof. Dotan received her medical degree from the Sackler Faculty of Medicine. Her post-doctoral fellowship was at the Immunobiology Center, Mount Sinai Medical Center, New York, NY, USA, where she focused on intestinal epithelial cell biology.
She is a specialist in internal medicine and in gastroenterology and liver diseases. Her clinical and research interests focus on biomarker-based stratification of patients with inflammatory bowel diseases and a personalized approach to their treatment and care, biologicals and novel therapies for inflammatory bowel disease, and the follow-up of ulcerative colitis patients before and after restorative proctocolectomy (pouch surgery), in a comprehensive, multidisciplinary pouch clinic.
Prof. Dotan conducts translational research in mucosal immunology, focusing on the interactions of intestinal epithelial cells and mucosal lymphocytes with their environment. Prof. Dotan first described the new anti-glycan antibodies and their relevance to Crohn’s disease a decade ago, and investigates the role of glycans in intestinal immune responses. Prof. Dotan published more than 100 papers in peer-reviewed journals. She is the Past President of the Israeli Association of Gastroenterology and Liver Diseases, a member of ECCO, the IOIBD, and the Immunology and IBD section of the American Gastroenterology Association (AGA).